Welcome to the Shiroguchi Lab !        - A Quantitative Omics Lab, Single Cell & Single Molecule Level -


    At the end of summer 2012, I moved to Yokohama from Boston, and started research at the RCAI (currently, RIKEN Center for Integrative Medical Sciences (IMS)). Now, I am at the RIKEN Quantitative Biology Center (QBiC, Osaka).
    I have been working in the fields of biophysics and genomics, mainly developing techniques to "see" the unknown. I would like to leverage my experience and skills to continue developing new techniques in order to understand biological systems and to contribute to discoveries in medical science and disease research. In particular, I am interested in seeing shifts in distributions, e.g. of cell states, by accurate system-wide measurements with single molecule and/or single cell resolution. This is important since heterogeneity in cell populations may be one of the key features in biological systems. For example, at the beginning of a disease, homeostasis may start to break down at the single cell level. We are working on some projects that go along this direction. We also are interested in the conbination of imaging technique and gene expression analyses.




Latest News


    Congratulations!
    Jianshi (Frank) Jin received Cold Spring Harbor Asia Fellowship Award in Tumor Immunology & Immunotherapy meeting

    Paper published
    "The efficacy and further functional advantages of random-base molecular barcodes for absolute and digital quantification of nucleic acid molecules"
    プレスリリース
    featured by newspapers, e.g.,    産経新聞    日本経済新聞

    Paper published

    Patent application     A provitional patent application filed

    Syposium participation     Japanese-American Frontiers of Science Symposium (JAFoS)